| Description | 24, 25-Dihydroxy VD2 (24,25-Dihydroxy vitamin D2) is a metabolite of vitamin D2, which is the isomer of vitamin D present in the body as 25-hydroxyvitamin D. PF-04957325 is used in the study of autoimmune encephalomyelitis. |
| Synonyms | 24,25-Dihydroxy vitamin D2 |
| molecular weight | 428.65 |
| Molecular formula | C28H44O3 |
| CAS | 58050-55-8 |
| Storage | keep away from direct sunlight,store under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 80 mg/mL (186.48 mM), Sonication is recommended. |
| References | 1. McGraw CA,et al. Simultaneous measurement of 25-hydroxy, 24,25-dihydroxy-, and 1,25-dihydroxyvitamin D without use of HPLC. Med Lab Sci. 1990 Jan;47(1):17-25. 2. Katsumi K,et al. Syntheses of 24,25-dihydroxyvitamin D2, 24,25-dihydroxy-22-dehydrovitamin D3, 25-hydroxy-24-oxo-22-dehydrovitamin D3 and 22,24,25-trihydroxyvitamin D3. Chem Pharm Bull (Tokyo). 1987 Mar;35(3):970-9. 3. Horst RL,et al. Impaired 24,25-dihydroxyvitamin D production in anephric human and pig. J Clin Invest. 1981 Jan;67(1):274-80. 4. Glenville Jones2,et al. Schnoes, Leon Levan et al.Isolation and identification of 24-hydroxyvitamin D2 and 24,25-dihydroxyvitamin D2. Archives of Biochemistry and Biophysics.Volume 202, Issue 2, July 1980, Pages 450-457 5. Glenville Jones, et al. Isolation and identification of 24,25-dihydroxy vitamin D2 by use of the perfused rat kidney. Biochemistry, 1979, 18 (6), pp 1094-1101 |