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2-Cyanopyrimidine

CAS No.: 14080-23-0

2-Cyanopyrimidine (m-Hydroxyphenylpropionic acid) is inhibitor of cathepsin K(IC50 : 170 nM)
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Description 2-Cyanopyrimidine (m-Hydroxyphenylpropionic acid) is inhibitor of cathepsin K(IC50 : 170 nM)
Target activity Cathepsin:170 nM
Synonyms 2-氰基嘧啶, 2-cyano-Pyrimidine
molecular weight 105.1
Molecular formula C5H3N3
CAS 14080-23-0
Storage Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility DMSO: 11 mg/mL (104.66 mM)
References 1. Rankovic Z , Cai J , Kerr J , et al. Optimisation of 2-cyano-pyrimidine inhibitors of cathepsin K: Improving selectivity over hERG[J]. Bioorganic and Medicinal Chemistry Letters, 2010, 20(21):6237-6241.