| Description | 2,2,2-Trichloroethanol is an agonist of the nonclassical K2P channels TREK-1 and TRAAK. |
| In vitro | 2,2,2-trichloroethanol dilated the middle cerebral artery and activated the potassium channel in cerebrovascular smooth muscle[1]. |
| molecular weight | 149.4 |
| Molecular formula | C2H3Cl3O |
| CAS | 115-20-8 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 55 mg/mL (368.14 mM) |
| References | 1. Nikhil K Parelkar , et al. 2,2,2-trichloroethanol Activates a Nonclassical Potassium Channel in Cerebrovascular Smooth Muscle and Dilates the Middle Cerebral Artery. J Pharmacol Exp Ther. 2010 Mar;332(3):803-10. |