| Description | (1R,2S)-VU0155041 is the cis regioisomer of VU0155041 and a partial agonist of mGluR4. |
| In vitro | (1R,2S)-VU0155041的效能与VU0155041在人类和大鼠受体上相当（人类mGluR4为798 nM，大鼠mGluR4为693 nM）。(1R,2S)-VU0155041（30 μM）在使用铊通量测定进行折算实验时，引起浓度依赖性的基线位移变化[1]。 |
| Target activity | mGluR4 (rat):(EC50)2.35 μM |
| molecular weight | 316.18 |
| Molecular formula | C14H15Cl2NO3 |
| CAS | 1263273-14-8 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 54 mg/mL (170.8 mM) |
| References | 1. Niswender CM, et al. Discovery, characterization, and antiparkinsonian effect of novel positiveallosteric modulators of metabotropic glutamate receptor 4. Mol Pharmacol. 2008 Nov;74(5):1345-58. |