| Description | 11β-HSD1 inibitor 19 shows inhibitory activities for hHSD1 and mHSD1 with IC50s of 16 nM and 10 nM. |
| Target activity | HSD1 (mouse):10 nM, HSD1 (human):16 nM |
| molecular weight | 461.86 |
| Molecular formula | C19H16ClF4N3O2S |
| CAS | 946400-19-7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 55 mg/mL (119.08 mM) |
| References | 1. Wan ZK, et al. Efficacious 11beta-hydroxysteroid dehydrogenase type I inhibitors in the diet-induced obesity mouse model. J Med Chem. 2009 Sep 10;52(17):5449-61. |