| Description | 1-Linoleoyl Glycerol (Monolinolein) is fatty acid glycerol that has been isolated from Saururus Chinensis roots. The (R)-1-Linoleoyl Glycerol and (S)-1-Linoleoyl Glycerol exhibit Lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitory activities with IC50 values of 45.0 and 52.0 μM, respectively. |
| Target activity | Lp-PLA2:45.0 μM((R)-1-Linoleoyl Glycerol), Lp-PLA2:52.0 μM((S)-1-Linoleoyl Glycerol) |
| Synonyms | Glycerol 1-monolinolate, Monolinolein, 一亚油酸甘油酯, Glyceryl monolinoleate, 1-Linoleoyl-rac-glycerol |
| molecular weight | 354.52 |
| Molecular formula | C21H38O4 |
| CAS | 2277-28-3 |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | Ethanol: 88 mg/mL (248.22 mM), Sonication is recommended. DMSO: 88 mg/mL (248.22 mM) |
| References | 1. Lee WS, et al. Lp-PLA2 inhibitory activities of fatty acid glycerols isolated from Saururus chinensis roots. Bioorg Med Chem Lett. 2005 Aug 1;15(15):3573-5. |