| Description | urolithin M6 (3,8,9,10-tetrahydroxy urolithin) (UM6) is an ellagitannin metabolite produced by gut microbiota, was identified as a putative galloflavin mimetic |
| In vitro | UM6 was investigated for its effect on lactic acid production and cell proliferation on Raji cell line. It exerted an evident effect on lactate production (IC50 = 36 ± 3 μM) and inhibited the cell growth with an IC50 of 25 ± 2 μM[1]. |
| Synonyms | 尿石素M6, 3,8,9,10-tetrahydroxy urolithin |
| molecular weight | 260.2 |
| Molecular formula | C13H8O6 |
| CAS | 1006683-97-1 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 65 mg/ml (249.81 mM) |
| References | 1. García-Villalba R, Selma MV, Espín JC, Tomás-Barberán FA. Identification of Novel Urolit Metabolites in Human Feces and Urine after the Intake of a Pomegranate Extract [published correction appears in J Agric Food Chem. 2020 Mar 11;68(10):3297]. J Agric Food Chem. 2019;67(40):11099-11107. doi:10.1021/acs.jafc.9b04435 |