Description | Timosaponin B III (Anemarsaponin BIII) is a bioactive steroidal saponin isolated from Anemarrhena asphodeloides Bge. Timosaponin B III possesses anti-inflammatory, anti-platelet aggregative and anti-depressive effects. |
Synonyms | Anemarsaponin BIII, 知母皂苷B3, 知母皂苷BIII |
molecular weight | 903.06 |
Molecular formula | C45H74O18 |
CAS | 142759-74-8 |
Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
References | 1. Zhao YF, et al. New transformation pathway and cytotoxic derivatives from the acid hydrolysis of timosaponin B III. Nat Prod Res. 2018 Nov 20:1-7. 2. Kang LP, et al. Steroidal glycosides from the rhizomes of Anemarrhena asphodeloides and their antiplateletaggregation activity. Planta Med. 2012 Apr;78(6):611-6. 3. Zhang XL, et al. Timosaponin B-III exhibits antidepressive activity in a mouse model of postpartum depression by the regulation of inflammatory cytokines, BNDF signaling and synaptic plasticity. Exp Ther Med. 2017 Oct;14(4):3856-3861. |