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Tetrahydropapaverine hydrochloride

CAS No.: 6429-04-5

Tetrahydropapaverine hydrochloride (Norlaudanosine HCl) , an analogue of salsolinol and tetrahydropapaveroline, has neur
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Description Tetrahydropapaverine hydrochloride (Norlaudanosine HCl) , an analogue of salsolinol and tetrahydropapaveroline, has neurotoxicity on dopamine neurons.
In vivo 在产生血清素的小鼠肥大细胞瘤P815细胞中,Tetrahydropapaverine可抑制血清素生物合成(IC50:7.5 μM),并降低色氨酸羟化酶活性(IC50:5.7 μM)。
Target activity TPH:5.7 μM
Synonyms Tetrahydropapaverine HCl, Norlaudanosine HCl, Tetrahydroalkali hydrochloride, 四氢罂粟碱盐酸盐
molecular weight 379.878
Molecular formula C20H26ClNO4
CAS 6429-04-5
Storage Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility DMSO: 60 mg/mL (157.94 mM)
References 1. Kim EI, et al. Life Sci, 2004, 75(16), 1949-1957. 2. Goto K, et al. Brain Res, 1997, 54(1-2), 260-268.