Description | Sec-O-Glucosylhamaudol (Hamaudol 3-glucoside) has anti-inflammatory effect through regulation of p38 Mitogen-Activated Protein Kinase in Lipopolysaccharide-stimulated RAW264.7 cell line. Intrathecal Sec-O-Glucosylhamaudol has a very strong antinociceptive effect in the formalin test and it seems the effect is related to an opioid receptor. |
Synonyms | 亥茅酚苷, Hamaudol 3-glucoside |
molecular weight | 438.43 |
Molecular formula | C21H26O10 |
CAS | 80681-44-3 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
Solubility | DMSO: 80 mg/mL(182.5 mM) Pyridine, Methanol, etc.: Soluble Ethanol: Soluble |
References | 1. Shen D, et al. Screening active components from Yu-ping-feng-san for regulating initiative key factors in allergic sensitization. PLoS One. 2014 Sep 8;9(9):e107279. 2. Kim SH, et al. Antinociceptive effect of intrathecal sec-O-glucosylhamaudol on the formalin-induced pain in rats. Korean J Pain. 2017 Apr;30(2):98-103. |