Taurodeoxycholic acid sodium hydrate-product

Description	Taurodeoxycholic acid sodium hydrate (Sodium taurodeoxycholate monohydrate), a hydrophilic bile salt, on bile salt and biliary lipid secretion in the rat.
In vivo	At all infusion rates, taurohyodeoxycholic acid caused a greater (P < 0.001) secretion of biliary lecithin compared to the other bile salts. There were no significant differences in the biliary secretion of cholesterol and proteins. Electron microscopy showed the recruitment of vesicles and lamellar bodies around and within bile canaliculi. In conclusion, taurohyodeoxycholic promotes a biliary lecithin secretion greater than expected from physicochemical predictions, representing a novel secretory property with potential pharmacological relevance[1].
Synonyms	Sodium taurodeoxycholate monohydrate, Taurodeoxychloic Acid sodium hydrate, Taurohyodeoxycholic acid sodium salt, 牛磺猪去氧胆酸
molecular weight	540.71
Molecular formula	C26H47NNaO7S
CAS	110026-03-4
Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year
Solubility	DMSO: 125 mg/mL (231.18 mM)
References	1. Angelico M , Baiocchi L , Nistri A , et al. Effect of taurohyodeoxycholic acid, a hydrophilic bile salt, on bile salt and biliary lipid secretion in the rat[J]. Digestive Diseases & Sciences, 1994, 39(11):2389-2397. 2. Roda A , Piazza F , Baraldini M , et al. Taurohyodeoxycholic acid protects against taurochenodeoxycholic acid–induced cholestasis in the rat[J]. Hepatology, 1998, 27.

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