| Description | Tamarixetin (4'-O-Methyl Quercetin) (4'-O-Methyl Quercetin) is a natural flavonoid derivative of quercetin, with anti-inflammatory and anti-oxidative effects. Tamarixetin protects against cardiac hypertrophy. |
| In vitro | Tamarixetin reduced the secretion of various inflammatory cytokines by dendritic cells after activation with LPS.?It also promoted the secretion of the anti-inflammatory cytokine interleukin (IL)-10 and specifically increased the population of IL-10-secreting immune cells in LPS-activated splenocytes.?Tamarixetin showed general anti-inflammatory effects in mouse models of bacterial sepsis and decreased bacteria abundance and endotoxin levels. |
| Synonyms | 柽柳黄素, 4'-O-Methyl Quercetin |
| molecular weight | 316.26 |
| Molecular formula | C16H12O7 |
| CAS | 603-61-2 |
| Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 4.4 mg/mL (13.91 mM) |
| References | 1. Jo P H , Jun L S , Joon C , et al. Tamarixetin Exhibits Anti-inflammatory Activity and Prevents Bacterial Sepsis by Increasing IL-10 Production[J]. Journal of Natural Products, 2018, 81:acs.jnatprod.8b00155-. |