| Description | Stearoyl-L-carnitine chloride (Acylcarnitine C18:0) is a long-chain acylcarnitine found in the cerebellum that inhibits GlyT2 and is an important component in the study of lipid metabolism. |
| Synonyms | C18 Carnitine, Stearoylcarnitine chloride |
| molecular weight | 464.12 |
| Molecular formula | C25H50ClNO4 |
| CAS | 32350-57-5 |
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 10 mg/mL (21.55 mM), Sonication is recommended. Ethanol: 20 mg/mL DMF: 20 mg/mL |
| References | 1. Cristofano A, et al. Serum Levels of Acyl-Carnitines along the Continuum from Normal to Alzheimer's Dementia. PLoS One. 2016 May 19;11(5):e0155694. 2. Carland JE, et al. Oleoyl-L-carnitine inhibits glycine transport by GlyTBr J Pharmacol. 2013 Feb;168(4):891-902. 3. Huang W, et al. Carnitine transport and its inhibition by sulfonylureas in human kidney proximal tubular epithelial cells. Biochem Pharmacol. 1999 Oct 15;58(8):1361-70. 4. Reuter, S.E., and Evans, A.M. Long-chain acylcarnitine deficiency in patients with chronic fatigue syndrome. Potential involvement of altered carnitine palmitoyltransferase-I activity. J. Intern. Med. 270(1), 76-84 (2011). |