| Description | Platycoside G1 (Deapi-platycoside E) may have anti-inflammatory effects. |
| In vitro | The change of the platycoside compositions was investigated after 1, 2, 3, 6 and 9h heat processing of Platycodi Radices by using HPLC coupled with an evaporative light scattering detection (ELSD) system. After heat treatment (125 °C, 1, 2, 3, 6 and 9 h), the contents of several platycosides such as platycoside E, platycodin D3, platycodin D, polygalacin D, and platycodin A decreased as the processing time was longer. While the total contents of the saponins decreased, the contents of deapi-forms of Deapi-platycoside E, deapi-platycodin D3, and deapi-platycodin D increased relatively. These results indicate that the linkage between apiose and xylose located at C-28 is labile to heat and pressure. The LPS-induced iNOS inhibitory activities of the samples treated for 1 and 2 hours were enhanced and after then, the activities were reduced. |
| Synonyms | 桔梗皂苷G1, Deapi-platycoside E |
| molecular weight | 1417.49 |
| Molecular formula | C64H104O34 |
| CAS | 849758-42-5 |
| Storage | store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 75 mg/mL (52.91 mM) |
| References | 1. Compositional analysis of major saponins and anti-inflammatory activitiy of steam-processed platycodi radix under pressure. Natural Product Sciences, 2008, 14(4):274-280. |