| Description | Pinobanksin 3-acetate (3-O-Acetylpinobanksin), a flavonoid derivative, is a strong antioxidant found in sunflowers and honey that inhibits LDL peroxidation. |
| In vitro | 两种新的苯丙烷基黄酮，(2R,3R)-6-[1-(4'-羟基-3'-甲氧基苯基)丙-2-烯-1-基]松果菊素（1）和(2R,3R)-6-[1-(4'-羟基-3'-甲氧基苯基)丙-2-烯-1-基]Pinobanksin 3-acetate（2），从墨西哥蜂胶的甲醇提取物中分离得到。这两种化合物（1，2）在缺乏营养的培养基中对PANC-1人类胰腺癌细胞显示出了选择性的细胞毒性活性，分别以17.9 μM和9.1 μM的浓度使50%的细胞优先死亡（PC₅₀值）。[1] |
| Target activity | PANC1 cells:17.9 μM, PANC1 cells:9.1 μM |
| Synonyms | 3-O-Acetylpinobanksin |
| molecular weight | 314.29 |
| Molecular formula | C17H14O6 |
| CAS | 52117-69-8 |
| Storage | store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 90.0 mg/mL (286.4 mM), Sonication is recommended. |
| References | 1. Li F, et al. Two new cytotoxic phenylallylflavanones from Mexican propolis. Chem Pharm Bull (Tokyo). 2011;59(9):1194-1196. 2. Xin BR, et al. A new flavonone from seeds of Alpinia katsumadai and its neuroprotective effect on PC12 cells. Zhongguo Zhong Yao Za Zhi. 2014;39(14):2674-2678. 3. Gobbo-Neto L, et al. Negative ion 'chip-based' nanospray tandem mass spectrometry for the analysis of flavonoids in glandular trichomes of Lychnophora ericoides Mart. (Asteraceae). Rapid Commun Mass Spectrom. 2008;22(23):3802-3808. l |