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Methyl 2,5-dihydroxycinnamate

CAS No.: 63177-57-1

Methyl 2,5-dihydroxycinnamate is an EGF receptor-associated tyrosine kinases inhibitor.
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Description Methyl 2,5-dihydroxycinnamate is an EGF receptor-associated tyrosine kinases inhibitor.
molecular weight 194.18
Molecular formula C10H10O4
CAS 63177-57-1
Storage Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Ethanol: 10 mg/ml(51.50 mM)
References 1. Sargeant P, Farndale RW, Sage SO. ADP- and thapsigargin-evoked Ca2+ entry and protein-tyrosine phosphorylation are inhibited by the tyrosine kinase inhibitors genistein and methyl-2,5-dihydroxycinnamate in fura-2-loaded human platelets. J Biol Chem. 1993 Aug 25;268(24):18151-6. 2. Sargeant P, Farndale RW, Sage SO. The tyrosine kinase inhibitors methyl 2,5-dihydroxycinnamate and genistein reduce thrombin-evoked tyrosine phosphorylation and Ca2+ entry in human platelets. FEBS Lett. 1993 Jan 11;315(3):242-6.