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Melianone

CAS No.: 6553-27-1

Melianone exhibits antiviral activity (EC50s: 3-11μM) against three important human pathogens, belonging to the Flavivi
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Description Melianone exhibits antiviral activity (EC50s: 3-11μM) against three important human pathogens, belonging to the Flaviviridae family, West Nile virus, Dengue virus, and Yellow Fever virus.
Synonyms NSC 302037, NSC-302037, NSC302037
molecular weight 470.68
Molecular formula C30H46O4
CAS 6553-27-1
Storage Powder: -20°C for 3 years | In solvent: -80°C for 1 year
References 1. Miguita CH, Barbosa Cda S, Hamerski L, Sarmento UC, Nascimento JN, Garcez WS, Garcez FR. 3β-O-tigloylmelianol from Guarea kunthiana: a new potential agent to control Rhipicephalus (Boophilus) microplus, a cattle tick of veterinary significance. Molecules. 2014 Dec 23;20(1):111-26. doi: 10.3390/molecules20010111. PubMed PMID: 25546624. 2. Vieira IJ, Azevedo Ode A, de Souza JJ, Braz-Filho R, Gonçalves Mdos S, de Araújo MF. Hirtinone, a Novel cycloartane-type triterpene and other compounds from Trichilia hirta L. (Meliaceae). Molecules. 2013 Feb 26;18(3):2589-97. doi: 10.3390/molecules18032589. PubMed PMID: 23442935. 3. Sanna G, Madeddu S, Giliberti G, Ntalli NG, Cottiglia F, De Logu A, Agus E, Caboni P. Limonoids from Melia azedarach Fruits as Inhibitors of Flaviviruses and Mycobacterium tubercolosis. PLoS One. 2015 Oct 20;10(10):e0141272. doi: 10.1371/journal.pone.0141272. eCollection 2015. PubMed PMID: 26485025; PubMed Central PMCID: PMC4612778. 4. Ntalli NG, Cottiglia F, Bueno CA, Alché LE, Leonti M, Vargiu S, Bifulco E, Menkissoglu-Spiroudi U, Caboni P. Cytotoxic tirucallane triterpenoids from Melia azedarach fruits. Molecules. 2010 Aug 27;15(9):5866-77. doi: 10.3390/molecules15095866. PubMed PMID: 20802401.