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Mauritianin

CAS No.: 109008-28-8

Mauritianin is a kaempferol glycoside isolated from the flowers and leaves of Acalypha indica and is a topoisomerase I i
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Description Mauritianin is a kaempferol glycoside isolated from the flowers and leaves of Acalypha indica and is a topoisomerase I inhibitor.Mauritianin has cytoprotective activity.
In vitro 生物活性引导的分级纯化导致了一种新的拓扑异构酶I抑制剂Mauritianin的分离。[1] 经过14周,Mauritianin在两阶段致癌过程的启动阶段,对抗了黄酮醇苷的细胞介导的免疫抑制作用。[3]
molecular weight 740.66
Molecular formula C33H40O19
CAS 109008-28-8
Storage store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility DMSO: 90.0 mg/mL (121.5 mM ), Sonication is recommended.
References 1. Ma J, et al. DNA topoisomerase I inhibitors from Rinorea anguifera.Bioorg Med Chem Lett. 2005 ; 15(3):813-816. 2. Nahrstedt A, et al. Flavonoids from Acalypha indica. Fitoterapia. 2006 ; 77(6):484-486. 3. Yasukawa K, et al. Inhibitory effects of flavonol glycosides on 12-O-tetradecanoylphorbol-13-acetate-induced tumor promotion. Chem Pharm Bull (Tokyo). 1990 ; 38(3):774-776.