| Description | Mauritianin is a kaempferol glycoside isolated from the flowers and leaves of Acalypha indica and is a topoisomerase I inhibitor.Mauritianin has cytoprotective activity. |
| In vitro | 生物活性引导的分级纯化导致了一种新的拓扑异构酶I抑制剂Mauritianin的分离。[1] 经过14周,Mauritianin在两阶段致癌过程的启动阶段,对抗了黄酮醇苷的细胞介导的免疫抑制作用。[3] |
| molecular weight | 740.66 |
| Molecular formula | C33H40O19 |
| CAS | 109008-28-8 |
| Storage | store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 90.0 mg/mL (121.5 mM ), Sonication is recommended. |
| References | 1. Ma J, et al. DNA topoisomerase I inhibitors from Rinorea anguifera.Bioorg Med Chem Lett. 2005 ; 15(3):813-816. 2. Nahrstedt A, et al. Flavonoids from Acalypha indica. Fitoterapia. 2006 ; 77(6):484-486. 3. Yasukawa K, et al. Inhibitory effects of flavonol glycosides on 12-O-tetradecanoylphorbol-13-acetate-induced tumor promotion. Chem Pharm Bull (Tokyo). 1990 ; 38(3):774-776. |