| Description | Apoptosis Inhibitor was a novel inhibitor of programmed cell death associate with caspase-3 inhibition. |
| In vitro | Apoptosis Inhibitor was identified as a novel inhibitor of apoptosis (programmed cell death) using an in vitro cell death assay system induced in human Fas-expressing WC8 cells by soluble human Fas ligand. |
| Synonyms | 2,2′-亚甲基双(1,3-环己二酮) |
| molecular weight | 236.26 |
| Molecular formula | C13H16O4 |
| CAS | 54135-60-3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 9 mg/mL(38.09mM) H2O: 0.1 mg/mL (insoluble) |
| References | 1. Tsuda T , Ohmori Y , Muramatsu H , et al. Inhibitory effect of M50054, a novel inhibitor of apoptosis, on anti-Fas-antibody-induced hepatitis and chemotherapy-induced alopecia.[J]. European Journal of Pharmacology, 2001, 433(1):37-45. |