| Description | Lycorine hydrochloride (Narcissine hydrochloride) is VE-cadherin inhibitor,and has IC50 of 1.2μM in Hey1B cell.It is an HCV inhibitor with strong activity. |
| Target activity | VE cadherin:1.2 μM |
| Synonyms | 石蒜碱, Licorine hydrochloride, Galanthidine hydrochloride, Narcissine hydrochloride, Lycorine chloride, Amarylline hydrochloride, 盐酸石蒜碱 |
| molecular weight | 323.77 |
| Molecular formula | C16H18ClNO4 |
| CAS | 2188-68-3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 50 mg/mL (154.43 mM) |
| References | 1. Hu M, et al. Oncotarget. 2015 Jun 20;6(17):15348-61. 2. Liang Q, Cai W, Zhao Y, et al. Lycorine ameliorates bleomycin-induced pulmonary fibrosis via inhibiting NLRP3 inflammasome activation and pyroptosis[J]. Pharmacological Research. 2020: 104884. 3. Ju X, Zhu Y, Wang Y, et al. A novel cell culture system modeling the SARS-CoV-2 life cycle[J]. PLoS pathogens. 2021, 17(3): e1009439. |