| Description | Icariside E5 may have antioxidant property that strengthen the importance of peppers in the Mediterranean diet. |
| In vitro | The chemical structures were elucidated mainly by extensive nuclear magnetic resonance methods and mass spectrometry, and the biological activities of icariside E(5) (4) were tested by different assays. Icariside E(5), in contrast to capsaicin, neither induces an increase in the intracellular levels of reactive oxygen species nor affects the mitochondria permeability transition, and it does not signal through the vanilloid receptor type 1. Interestingly, this compound protects Jurkat cells from apoptosis induced by the oxidative stress mediated by serum withdrawal. |
| Synonyms | 淫羊藿次甙E5, 淫羊藿次甙 E5 |
| molecular weight | 522.54 |
| Molecular formula | C26H34O11 |
| CAS | 126176-79-2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. New glycosides from Capsicum annuum L. var. acuminatum. Isolation, structure determination, and biological activity.J Agric Food Chem. 2001 Apr;49(4):2022-9. |