| Description | Hydroxysafflor yellow A (Safflomin A) inhibited adipogenesis by increasing HSL promoter activities. Hydroxysafflor yellow A can effectively protect the liver from long-term alcohol injury by enhancing antioxidant capacity and inhibiting the expression of TGF-β. It prevents steroid-induced avascular necrosis of femoral head by inhibiting primary bone marrow-derived mesenchymal stromal cells. Also, Hydroxysafflor yellow A has anti-tumor effects. |
| Synonyms | 藏红花, 羟基红花黄色素A, HSYA, Safflomin A |
| molecular weight | 612.53 |
| Molecular formula | C27H32O16 |
| CAS | 78281-02-4 |
| Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 50 mg/mL (81.63 mM) |
| References | 1. Zhu HJ, et al. Cytotechnology. 2015 Oct;67(5):885-92. 2. Yang F, et al. Eur J Pharmacol. 2015 May 5;754:105-14. 3. He Y, et al. J Physiol Biochem. 2015 Mar;71(1):69-78. 4. Liu YL, et al. Int Immunopharmacol. 2014 Dec;23(2):649-57. 6. Jin M, et al. Hydroxysafflor yellow A attenuate lipopolysaccharide-induced endothelium inflammatory injury. Chin J Integr Med. 2015 May 27. 7. Miao T, Qian L, Yu F, et al. Protective effects of hydroxysafflor yellow an on high oxidized low density lipoprotein induced human coronary artery endothelial cells injuries. development. 2019, 22: 581-589. |