| Description | β-Elemonic Acid (3-Oxotirucallenoic Acid) exhibits anti-inflammatory effects. Beta-Elemonic acid inhibits proliferation by inducing hypoploid cells and cell apoptosis, the anticancer effects of beta-Elemonic acid are related to the MAPK signaling pathway, ROS activation and glutathione depletion in human A549 lung cancer cells. Beta-Elemonic acid exhibits prolyl endopeptidase inhibitory activities. |
| Synonyms | 3-oxo Tirucallic Acid, β-岚香酮酸, Beta-Elemonic acid, 3-Oxotirucallenoic Acid, β-榄香酮酸, Elemadienonic Acid |
| molecular weight | 454.68 |
| Molecular formula | C30H46O3 |
| CAS | 28282-25-9 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 45.45 mg/ml(99.97mM), Sonication is recommended. Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.: Soluble |
| References | 1. Wu T T , Lu C L , Lin H I , et al. β-Elemonic acid inhibits the cell proliferation of human lung adenocarcinoma A549 cells: The role of MAPK, ROS activation and glutathione depletion[J]. Oncology Reports, 2016, 35(1):227-234. |