| Description | Geranylgeraniol (FT0626663) is an isoprenoid found in fruits, vegetables, and grains, including rice. Geranylgeraniol (FT0626663) inhibits growth and induces apoptosis of various tumor cells. Geranylgeraniol (FT0626663) protects monocytes against statin-induced cytotoxicity and suppresses the growth of Mycobacterium. |
| Synonyms | FT-0626663, Tetraprenol, CJ24095, CJ 24095, FT0626663, 香叶基香叶醇, CJ-24095 |
| molecular weight | 290.48 |
| Molecular formula | C20H34O |
| CAS | 24034-73-9 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | Ethanol: >25 mg/ml |
| References | 1. Schumacher MM, et al. The prenyltransferase UBIAD1 is the target of geranylgeraniol in degradation of HMG CoA reductase. Elife. 2015 Mar 5;4. 2. Fernandes NV, et al. Geranylgeraniol suppresses the viability of human DU145 prostate carcinoma cells and the level of HMG CoA reductase. Exp Biol Med (Maywood). 2013 Nov 1;238(11):1265-74. 3. Zafar S, et al. Zoledronic acid and geranylgeraniol regulate cellular behaviour and angiogenic gene expression in human gingival fibroblasts. J Oral Pathol Med. 2014 Oct;43(9):711-21. 4. Pabst AM, et al. Isoprenoid geranylgeraniol: the influence on cell characteristics of endothelial progenitor cells after bisphosphonate therapy in vitro. Clin Oral Investig. 2015 Sep;19(7):1625-33. |