| Description | Galanthamine (Galantamine) is an acetylcholinesterase (AChE)inhibitor(IC50 : 500 nM), can reduce brain damage induced by hypoxia-ischemia. |
| In vivo | Galanthamine 是一种选择性、可逆的竞争性乙酰胆碱酯酶抑制剂，已被批准用于阿尔茨海默病的症状治疗[1]。 |
| Target activity | AChE:500 nM |
| Synonyms | Galantamine, 加兰他敏 |
| molecular weight | 287.35 |
| Molecular formula | C17H21NO3 |
| CAS | 357-70-0 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 58.82 mg/ml (204.71.mM ) |
| References | 1. Luis Marco M D C C . Galanthamine, a Natural Product for the Treatment of Alzheimer's Disease[J]. Recent Patents on Cns Drug Discovery, 2006, 1(1):p.105-111. 2. S López-Pousa, Garre-Olmo J , Vilalta-Franch J . [Galanthamine versus donepezil in the treatment of Alzheimer's disease][J]. Revista De Neurologia, 2007, 44(11):677-684. |