| Description | Fraxinol is a predicted metabolite generated by BioTransformer1 that is produced by the metabolism of 5, 7-dimethoxy-2h-chromen-2-one. It is generated by cyp1a2, cyp2a6, cyp2b6, cyp2c9, cyp2c19, and cyp2e1 enzymes via an aromatic-hydroxylation-of-fused-benzene-ring-pattern1 reaction. |
| molecular weight | 222.19 |
| Molecular formula | C11H10O5 |
| CAS | 486-28-2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 60 mg/mL (270.03 mM) Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.: Soluble |
| References | 1. Hammoda, H., Ela, M., El-Lankany, A., El-Hanbali, O., Zaki, C., & Ghazy, N. (2008). New constituents of Artemisia monosperma Del. Pharmazie., 63(8), 611-4. 2. Riveiro, M., Maes, D., Vázquez, R., Vermeulen, M., Mangelinckx, S., & Jacobs, J. et al. (2009). Toward establishing structure–activity relationships for oxygenated coumarins as differentiation inducers of promonocytic leukemic cells. Bioorganic & Medicinal Chemistry, 17(18), 6547-6559. doi: 10.12016/j.bmc.2009.08.2002 |