| Description | DL-Syringaresinol ( (±)-Syringaresinol) is a lignan from ginseng berries with anti-inflammatory, antioxidant, analgesic and weak anti-mycobacterial activities.DL-Syringaresinol can delay oxidative stress-induced skin aging through autophagy, alleviate oxaliplatin-induced neuropathic pain and sepsis-induced cardiac dysfunction by inhibiting inflammatory responses. neuropathic pain and sepsis-induced cardiac dysfunction by inhibiting inflammatory responses. |
| In vitro | A methanol extract from unripe Japanese apricot showed inhibitory activity of Helicobacter pylori motility. Inhibitory compound 1 was isolated and identified as (+)-syringaresinol (1) by spectoroscopic means. (+)-Syringaresinol (1) inhibited >90% of the H. pylori motility at a concentration of 500 microg/ml and the IC50 value was 50 microg/ml[1] |
| Synonyms | (±)-Syringaresinol |
| molecular weight | 418.44 |
| Molecular formula | C22H26O8 |
| CAS | 1177-14-6 |
| Storage | store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 4.18 mg/ml (10 mM) Methanol: 4.18 mg/ml (10 mM), Sonication is recommended. |
| References | 1. Jung Hwan Oh, et al. Syringaresinol Inhibits UVA-Induced MMP-1 Expression by Suppression of MAPK/AP-1 Signaling in HaCaT Keratinocytes and Human Dermal Fibroblasts. Int J Mol Sci. 2020 Jun 1;21(11):3981. 2. Su-Yen Chang, et al. Antimycobacterial butanolides from the root of Lindera akoensis. Chem Biodivers. 2008 Dec;5(12):2690-8. |