| Description | Dihydrodaidzein ((±)-Dihydrodaidzein)-producing bacteria might lead to clarification of some of the mechanisms regulating the production of equol by fecal microbiota. |
| In vitro | Recently, we isolated a Dihydrodaidzein (DHD)-producing Clostridium-like bacterium, strain TM-40, from human feces. We investigated the effects of strain TM-40 on in vitro daidzein metabolism by human fecal microbiota from a male equol producer and two male equol non-producers. In the fecal suspension from the male equol non-producer and DHD producer, DHD was detected in the in vitro fecal incubation of daidzein after addition of TM-40. The DHD concentration increased as the concentration of strain TM-40 increased. In the fecal suspension from the equol producer, the fecal equol production was increased by the addition of strain TM-40. The occupation ratios of Bifidobacterium and Lactobacillales were higher in the equol non-producers than in the equol producer. Adding isoflavone-metabolizing bacteria to the fecal microbiota should facilitate the estimation of the metabolism of isoflavonoids by fecal microbiota[1] |
| Synonyms | 二氢7-羟基-3-(4-羟苯基)-4-苯并吡喃酮, 二氢大豆苷元, (±)-Dihydrodaidzein |
| molecular weight | 256.25 |
| Molecular formula | C15H12O4 |
| CAS | 17238-05-0 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 100 mg/mL (390.24 mM), Sonication is recommended. |
| References | 1. Dihydrodaidzein-producing Clostridium-like intestinal bacterium, strain TM-40, affects in vitro metabolism of daidzein by fecal microbiota of human male equol producer and non-producers.Biosci Microflora. 2011;30(3):65-71. |