| Description | Epmedin C (Baohuoside-VI) was metabolized via desugarization, dehydrogenation, hydrogenation, dehydroxylation, hydroxylation, demethylation and glucuronidation pathways in vivo. It has potential activity against osteoporosis by stimulating osteoblasts. |
| Synonyms | 淫羊霍定C, Baohuoside-VI, Epimedin C |
| molecular weight | 822.8 |
| Molecular formula | C39H50O19 |
| CAS | 110642-44-9 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 50 mg/mL (60.77 mM) |
| References | 1. Cui L, et al. Biomed Chromatogr. 2014 Oct;28(10):1306-12. 2. Liu M, et al. J Sep Sci. 2011 Nov;34(22):3200-7. 3. Li Y, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2005 Jul 25;821(2):235-9. 4. Gao Y, Xu G, Ma L, et al. Icarisid I specifically facilitates ATP or nigericin-induced NLRP3 inflammasome activation and causes idiosyncratic hepatotoxicity[J]. Cell Communication and Signaling. 2020 5. Gao Y, Xu G, Ma L, et al. Icariside I specifically facilitates ATP or nigericin-induced NLRP3 inflammasome activation and causes idiosyncratic hepatotoxicity[J]. Cell Communication and Signaling. 2021, 19(1): 1-14. |