| Description | Dihydrocucurbitacin B (23,24-dihydrocucurbitacin B) is isolated from the roots of Cayaponia tayuya with anti-cancer activity. |
| In vitro | Dihydrocucurbitacin B抑制NFAT和延迟型超敏反应,同时在G0期引起细胞周期停滞[2]。 |
| Synonyms | 二氢葫芦素 B, 23,24-dihydrocucurbitacin B |
| molecular weight | 560.72 |
| Molecular formula | C32H48O8 |
| CAS | 13201-14-4 |
| Storage | store at low temperature,keep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Lang KL, et al. Synthesis and cytotoxic activity evaluation of dihydrocucurbitacin B and cucurbitacin B derivatives. Bioorg Med Chem. 2012 May 1;20(9):3016-30. 2. Escandell JM, et al. Dihydrocucurbitacin B inhibits delayed type hypersensitivity reactions by suppressing lymphocyte proliferation. J Pharmacol Exp Ther. 2007 Sep;322(3):1261-8. |