| Description | D-Thyroxine (Dextroxin) could lower cholesterol and also increases hepatic lipase which in turn improves utilization of triglycerides, leading to improve apolipoprotein E cholesterol particles. |
| Synonyms | Dethyrona, Detyroxin, Dextroid, Dextrothyroxine;Biotirmone, Dextroxin, Biotirmone, Debetrol, Dextrothyroxine |
| molecular weight | 776.87 |
| Molecular formula | C15H11I4NO4 |
| CAS | 51-49-0 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | H2O: Insoluble DMSO: 55 mg/ml (70.8 mM) |
| References | 1. Schwartz ID, Bercu BB. Dextrothyroxine in the treatment of generalized thyroid hormone resistance in a boy homozygous for a defect in the T3 receptor. Thyroid. 1992 Spring;2(1):15-9. PubMed PMID: 1525565. 2. Krawczynska H, Wojcik-Musialek K, Illig R. 10 years of successful treatment with dextrothyroxine in a girl with TSH-induced hyperthyroidism. Horm Res. 1991;35(5):213-6. PubMed PMID: 1802825. 3. Hazenberg HJ, Muller CJ, Kerckhoffs HP, Erkelens DW. Dextrothyroxine induced hyperthyroidism in a patient with heterozygous familial hypercholesterolaemia. Neth J Med. 1987 Oct;31(3-4):117-21. PubMed PMID: 3683682. 4. Hankins JH, Heise CM, Cowan RJ. Iatrogenic hyperthyroidism secondary to dextrothyroxine administration. Clin Nucl Med. 1984 Jan;9(1):17-9. PubMed PMID: 6697613. |