| Description | Asebogenin is a compound fractionated from Salvia miltiorrhiza with antifungal activity, inhibition of GPVI-induced platelet reactions, and inhibition of NET formation induced by pro-inflammatory stimuli. |
| In vitro | Asebogenin抑制了一系列GPVI引发的血小板反应，并抑制了由促炎刺激引起的NETs形成。从机制上讲，Asebogenin直接干预了Syk在Tyr525/526[1]的磷酸化。 |
| molecular weight | 288.3 |
| Molecular formula | C16H16O5 |
| CAS | 520-42-3 |
| Storage | store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Polat MF. Synthesis of Asebogenin and Balsacone A Precursor by a Novel Synthetic Strategy: Recent Opportunities for and Challenges of Total Synthesis of Balsacone A. Molecules. 2022 May 30;27(11):3523. 2. Li L,et al. Asebogenin suppresses thrombus formation via inhibition of Syk phosphorylation. Br J Pharmacol. 2023 Feb;180(3):287-307. |