| Description | 3-Acetyl-beta-boswellic acid has antitumor activity, it inhibits synthesis of DNA, RNA and protein in human leukemia HL-60 cells in a dose dependent manner with IC50 values ranging from 0.6 to 7.1 microM. |
| In vitro | They inhibited the synthesis of DNA, RNA and protein in human leukemia HL-60 cells in a dose dependent manner with IC50 values ranging from 0.6 to 7.1 microM. Among them, compound 4 induced the most pronounced inhibitory effects on DNA, RNA and protein synthesis with IC50 values of 0.6, 0.5, and 4.1 microM, respectively. |
| Synonyms | 3-O-Acetyl-beta-boswellic acid, 3-乙酰基-BETA-乳香酸 |
| molecular weight | 498.74 |
| Molecular formula | C32H50O4 |
| CAS | 5968-70-7 |
| Storage | store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 11 mg/mL (22.06 mM) |
| References | 1. Inhibitory activity of boswellic acids from Boswellia serrata against human leukemia HL-60 cells in culture.Planta Med. 1998 May;64(4):328-31. |