| Description | 2-Methoxyestrone is a methoxylated catechol estrogen and the principal metabolite of 2-hydroxyestrone, a nonuterotropic metabolite of estradiol. |
| In vivo | 在发情前期的中午给予2-Methoxyestrone，显著增加了排卵前催乳素水平的上升幅度，这可能是通过抑制大脑中内源性2-hydroxyestrogens的形成实现的[2]。 |
| molecular weight | 300.39 |
| Molecular formula | C19H24O3 |
| CAS | 362-08-3 |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 44 mg/mL (146.48 mM) |
| References | 1. Lewis KM, et al. pKa values of estrone, 17 beta-estradiol and 2-methoxyestrone. Steroids. 1979 Nov;34(5):485-99. 2. Katayama S, Fishman J. 2-Hydroxyestrone suppresses and 2-methoxyestrone augments the preovulatory prolactin surge in the cycling rat. Endocrinology. 1982 Apr;110(4):1448-50. |