| Description | 1,2,4-Trihydroxybenzene (Benzene-1,2,4-triol) is a by-product of coffee bean roasting and is found in mouse, arabica coffee.1,2,4-Trihydroxybenzene is a benzotriol that increases Ca2+ concentration in rat thymic lymphocytes. |
| Synonyms | Benzene-1,2,4-triol |
| molecular weight | 126.11 |
| Molecular formula | C6H6O3 |
| CAS | 533-73-3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 60 mg/mL (475.78 mM), Sonication is recommended. |
| References | 1. Kamae R, et al. Hydroxyhydroquinone, a by-product of coffee bean roasting, increases intracellular Ca2+ concentration in rat thymic lymphocytes. Food Chem Toxicol. 2017;102:39-45. 2. Kato H, et al. Characterization of two 1,2,4-trihydroxybenzene 1,2-dioxygenases from Phanerochaete chrysosporium. Appl Microbiol Biotechnol. 2022;106(12):4499-4509. 3. Reichenbecher W, et al. Hydroxyhydroquinone reductase, the initial enzyme involved in the degradation of hydroxyhydroquinone (1,2,4-trihydroxybenzene) by Desulfovibrio inopinatus. Arch Microbiol. 2000;173(3):206-212. |