Bioactivity | β-Melanocyte Stimulating Hormone (MSH), human, a 22-residue peptide, acts as an endogenous melanocortin-4 receptor (MC4-R) agonist[1]. |
Target | Melanocortin-4 receptor (MC4-R) |
Invitro | β-Melanocyte Stimulating Hormone (MSH), human (β-MSH) has high affinity at both human MC4-R transfected into CHO cells (Ki=11.4±0.4 nM) and MC4-R in rat hypothalamic homogenates (Ki=5.0±0.4 nM)[1]. |
Name | β-Melanocyte Stimulating Hormone (MSH), human |
CAS | 17908-57-5 |
Sequence | Ala-Glu-Lys-Lys-Asp-Glu-Gly-Pro-Tyr-Arg-Met-Glu-His-Phe-Arg-Trp-Gly-Ser-Pro-Pro-Lys-Asp |
Shortening | AEKKDEGPYRMEHFRWGSPPKD |
Formula | C118H174N34O35S |
Molar Mass | 2660.92 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Harrold JA, et al. beta-MSH: a functional ligand that regulated energy homeostasis via hypothalamic MC4-R? Peptides. 2003 Mar;24(3):397-405. |