Tat-peptide 190-208_product_DataBase

Bioactivity	Tat-peptide 190-208 is a cell-permeable and Tat-labeled fusion peptide, corresponding to residues 190-208 of rat G3BP1. Tat sequence from HIV, is placed at the least conserved end of the sequence, for cell permeability. Tat-peptide 190-208 increases axon growth and increases the number of neurites per neuron. Tat-peptide 190-208 likely exhibits an axon intrinsic mechanism. Tat-peptide 190-208 can be used for ischemic protection during endovascular repair for intracranial aneurysms[1].
Invitro	Tat-peptide 190-208 (10 μM、20 μM；24 小时) 在分离的 DRG 培养物中增加轴突长度 10 μM，在 iMotor 神经元中增加 20 μM[1]。Tat-peptide 190-208 (10 μM；3 天) 增加从每个神经元延伸的轴突总数[1]。
Name	Tat-peptide 190-208
Sequence	Tyr-Gly-Asn-Lys-Lys-Asn-Asn-Gln-Asn-Asn-Asn-Val-Ala-Glu-Pro-Glu-Pro-Asp-Pro-Glu-Pro-Glu-Pro-Glu-Gln-Glu-Pro-Val-Ser-Glu
Shortening	YGNKKNNQNNNVAEPEPDPEPEPEQEPVSE
Formula	C142H214N40O57
Molar Mass	3393.45
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Sahoo PK, et al. Axonal G3BP1 stress granule protein limits axonal mRNA translation and nerve regeneration.

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