| Bioactivity | Pirepemat (IRL752) is a corticalpreferring catecholamine- and cognition-promoting agent. Pirepemat (IRL752) is used for the study of Parkinson's disease[1][2]. | ||||||||||||
| Invitro | IRL752 displayed its highest in vitro affinities for 5-HT and NA-related targets[2]. | ||||||||||||
| In Vivo | IRL752 (3.7-100 µmol/kg, s.c.) has no significant effect on acute hyper-dopaminergic or hypo-glutamatergic motor responses, but reversed deficits resulting from hypomonoaminergic function[2]. Animal Model: | ||||||||||||
| Name | Pirepemat | ||||||||||||
| CAS | 1227638-29-0 | ||||||||||||
| Formula | C11H13F2NO | ||||||||||||
| Molar Mass | 213.22 | ||||||||||||
| Appearance | Oil | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
|
||||||||||||
| Reference | [1]. Ipsen and IRLAB Enter Exclusive Worldwide Licensing Agreement Aimed to Improve the Lives of People Living with Parkinson's Disease. [2]. S Hjorth, et al. (3 S)-3-(2,3-difluorophenyl)-3-methoxypyrrolidine (IRL752) -a Novel Cortical-Preferring Catecholamine Transmission- and Cognition-Promoting Agent. J Pharmacol Exp Ther. 2020 Sep;374(3):404-419. |
Pirepemat
CAS: 1227638-29-0 F: C11H13F2NO W: 213.22
Pirepemat (IRL752) is a corticalpreferring catecholamine- and cognition-promoting agent. Pirepemat (IRL752) is used for
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.