| Bioactivity | PLP (139-151) is amino acid residue 139 to 151 of myelin proteolipid protein (PLP) used to induce experimental autoimmune encephalomyelitis (EAE). | ||||||
| Invitro | Severe clinical and histological EAE could be induced by adoptive transfer of the peptide-specific T cell line and 3 of 4 T cell clones. The T cell line/clones all responded strongly to PLP (139-151) in in vitro proliferative assays. Line SPL and all of the clones show strong proliferative response to the whole PLP molecule and to PLP (139-151)[1]. | ||||||
| Name | PLP (139-151) | ||||||
| CAS | 131334-43-5 | ||||||
| Sequence | His-Cys-Leu-Gly-Lys-Trp-Leu-Gly-His-Pro-Asp-Lys-Phe | ||||||
| Shortening | HCLGKWLGHPDKF | ||||||
| Formula | C72H104N20O16S | ||||||
| Molar Mass | 1537.79 | ||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||
| Storage | Sealed storage, away from moisture
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
PLP (139-151)
CAS: 131334-43-5 F: C72H104N20O16S W: 1537.79
PLP (139-151) is amino acid residue 139 to 151 of myelin proteolipid protein (PLP) used to induce experimental autoimmun
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