| Bioactivity | Lanreotide (BIM 23014) acetate is a somatostatin analogue with antineoplastic activity. Lanreotide acetate can be used for the research of carcinoid syndrome[1][2]. | ||||||
| Invitro | Lanreotide (BIM 23014) (100 nM; 0-48 h) enhanced radiation-induced apoptosis[1].Lanreotide results in a dose-dependent decrease in GH3 cell colony forming units. Lanreotide at concentrations of 1, 10, 100, and 1000 nM results in cell survival rates of 75, 56, 39 and 27% respectively. The IC50 is 57 nM[1].Lanreotide inhibits GH-secreting pituitary adenoma cell proliferation and hormone release in vitro[2]. Apoptosis Analysis[1] Cell Line: | ||||||
| Name | Lanreotide acetate | ||||||
| CAS | 2378114-72-6 | ||||||
| Sequence | {d-2nal}-Cys-Tyr-{d-Trp}-Lys-Val-Cys-Thr-NH2 (Disulfide bridge: Cys2-Cys7) | ||||||
| Shortening | {d-2nal}-CY-{d-Trp}-KVCT-NH2 (Disulfide bridge: Cys2-Cys7) | ||||||
| Formula | C56H73N11O12S2 | ||||||
| Molar Mass | 1156.38 | ||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||
| Storage | Sealed storage, away from moisture and light, under nitrogen
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen) |
Lanreotide acetate
CAS: 2378114-72-6 F: C56H73N11O12S2 W: 1156.38
Lanreotide (BIM 23014) acetate is a somatostatin analogue with antineoplastic activity. Lanreotide acetate can be used f
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