| Bioactivity | Isoglobotriaose (Gala-3Galb-4Glc) is a glycosphingolipid found in mammalian tissues. Isoglobotriaose is an analogue of Globotriaose, the ganglioside derivatives of them locate in difference position of small intestine, isoglobotriaosylceramide is restricted to the nonepithelial residue, while globotriaosylceramide is in both compartments[1][2]. |
| Invitro | Isoglobotriaose is synthesized from lactose, glucose-1-phophate (Glc-1-P), and uridine 5’-triphosphate (UTP) by a one-pot three-enzyme system containing UDP-glucose pyrophosphorylase (GlaU), UDP-Gal 4-epimerase (GalE), and an α1-3galactosytransferase (α1-3GalT)[1]. |
| Name | Isoglobotriaose |
| CAS | 41744-59-6 |
| Formula | C18H32O16 |
| Molar Mass | 504.44 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Li W, et al. Strategies for chemoenzymatic synthesis of carbohydrates. Carbohydr Res. 2019 Jan 15;472:86-97. [2]. Breimer ME, et al. Glycosphingolipids of rat tissues. Different composition of epithelial and nonepithelial cells of small intestine. J Biol Chem. 1982 Jan 10;257(1):557-68. |
Isoglobotriaose
CAS: 41744-59-6 F: C18H32O16 W: 504.44
Isoglobotriaose (Gala-3Galb-4Glc) is a glycosphingolipid found in mammalian tissues. Isoglobotriaose is an analogue of G
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