| Bioactivity | Hydralazine hydrochloride is a orally active antihypertensive agent, reduces peripheral resistance directly by relaxing the smooth muscle cell layer in arterial vessel. Hydralazine hydrochloride has antioxidant activity, as well as inhibits ROS release and O2·- generation with an IC50 value of 9.53 mM and 1.19 mM, respectively[1][2]. |
| Target | IC50: 9.53 mM (ROS), 1.19 mM (O2·-) |
| Name | Hydralazine hydrochloride |
| CAS | 304-20-1 |
| Formula | C8H9ClN4 |
| Molar Mass | 196.64 |
| Appearance | Solid |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
| Reference | [1]. Bourreli, B., et al., Additive effects of dihydralazine during enflurane or isoflurane hypotensive anaesthesia for spinal fusion. Can J Anaesth, 1988. 35(3 ( Pt 1)): p. 242-8. [2]. Kandler, M.R., et al., Hydralazine for essential hypertension. Cochrane Database Syst Rev, 2010(8): p. CD004934. |
Hydralazine hydrochloride
CAS: 304-20-1 F: C8H9ClN4 W: 196.64
Hydralazine hydrochloride is a orally active antihypertensive agent, reduces peripheral resistance directly by relaxing
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