| Bioactivity | Hyaluronan synthase is a membrane protein that requires only Mg+2 and two sugar-UDP substrates (GlcUA-UDP and GlcNAc-UDP) to polymerize HA chains. Hyaluronan synthase catalyzes the biosynthesis of hyaluronic acid (HA)[1][2]. |
| Name | Hyaluronan synthase (PmHAS) |
| CAS | 39346-43-5 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Agarwal G, et al. Biosynthesis of Hyaluronic acid polymer: Dissecting the role of sub structural elements of hyaluronan synthase. Sci Rep. 2019 Aug 29;9(1):12510. [2]. Weigel PH. Hyaluronan Synthase: The Mechanism of Initiation at the Reducing End and a Pendulum Model for Polysaccharide Translocation to the Cell Exterior. Int J Cell Biol. 2015;2015:367579. |