| Bioactivity | Dioxone is a substance possessing convulsant properties qualitatively similar to leptazol and bemegride. Dioxone is orally active[1]. |
| Invitro | Dioxone is soluble in ethanol, ether, chloroform and propylene glycol. A 1 percent aqueous solution may be obtained at room temperature giving a pH of 4.3, and, with warming to 50℃, 2 percent aqueous solutions may be prepared[1]. |
| In Vivo | Dioxone (0-30 mg/kg; i.v., i.p., oral, s.c.; once) induces convulsant action[1]. Animal Model: |
| Name | Dioxone |
| CAS | 702-54-5 |
| Formula | C8H13NO3 |
| Molar Mass | 171.19 |
| Appearance | Solid |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |
| Reference | [1]. G MAFFII, et al. A new analeptic: 5, 5-diethyl-1, 3-oxazine-2,4-dione (Dioxone). J Pharm Pharmacol. 1961 Apr;13:244-53. |