| Bioactivity | Cinepazide is a piperazine derivative and acts as a weak calcium channel blocker. Cinepazide is a potent vasodilator and can be used for the research of cerebrovascular diseases, including ischemic stroke, brain infarct et. al[1]. |
| In Vivo | Cinepazide (intravenous injection; 30 mg/kg) potentiates the vertebral vasodilator response of dogs to intravertebral adenosine and cyclic AMP, while cinnarizine reduces their vasodilator effects[1].Cinepazide (intravertebral injection; 1-10 mg/kg) increases vertebral blood flow in a dose-related manner and the effect is partially inhibited by Aminophylline (HY-B0140) in dogs[1]. |
| Name | Cinepazide |
| CAS | 23887-46-9 |
| Formula | C22H31N3O5 |
| Molar Mass | 417.50 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Akashi, A., et al., [Cardiovascular pharmacology of cinepazide, a new cerebral vasodilator (author's transl)]. Nihon Yakurigaku Zasshi, 1979. 75(5): p. 507-16. [2]. Jonathan G Swoboda, et al. Small molecule mediated proliferation of primary retinal pigment epithelial cells. ACS Chem Biol. 2013 Jul 19;8(7):1407-11. |
Cinepazide
CAS: 23887-46-9 F: C22H31N3O5 W: 417.50
Cinepazide is a piperazine derivative and acts as a weak calcium channel blocker. Cinepazide is a potent vasodilator and
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This product is for research use only, not for human use. We do not sell to patients.