| Bioactivity | C/EBPα inducer 1 (compound 78) is a potent inducer of C/EBPα and myeloid differentiation[1]. | |||||||||
| Invitro | C/EBPα inducer 1 (compound 78, 3 μM) causes myeloid differentiation differentiation[1].C/EBPα inducer 1 (compound 78) increases the expression of the neutrophil differentiation surface marker CD11b[1].C/EBPα inducer 1 (compound 78) induces the expression of the neutrophil differentiation surface marker CD11b and upregulation of CEBPA and its downstream targets[1].C/EBPα inducer 1 (compound 78) can upregulate G-CSF receptors, and render leukemic cells more sensitive to G-CSF stimulation[1]. | |||||||||
| Name | C/EBPα inducer 1 | |||||||||
| CAS | 2374285-52-4 | |||||||||
| Formula | C20H12FN3O4 | |||||||||
| Molar Mass | 377.33 | |||||||||
| Appearance | Solid | |||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | |||||||||
| Storage |
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| Reference | [1]. Radhakrishnan Sridhar, et al. Styryl Quinazolinones as Potential Inducers of Myeloid Differentiation via Upregulation of C/EBPα. Molecules. 2018 Aug 3;23(8):1938. |