Bioactivity | Bis-propargyl-PEG3 is a PEG-based PROTAC linker used in the synthesis of PROTACs. Bis-propargyl-PEG3 is used in the synthesis of zinc-dipicolylamine (ZnDPA) complexes with antiplasmodial activity[1] [2]. | ||||||||||||
Invitro | Bis-propargyl-PEG3 is used in the synthesis of zinc-dipicolylamine (ZnDPA) complexes with antiplasmodial activity against three strains of Plasmodium falciparum [2]. | ||||||||||||
Name | Bis-propargyl-PEG3 | ||||||||||||
CAS | 126422-58-0 | ||||||||||||
Formula | C12H18O4 | ||||||||||||
Molar Mass | 226.27 | ||||||||||||
Appearance | Liquid | ||||||||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
Storage |
|
||||||||||||
Reference | [1]. Pearlie BURNETTE, et al. Dimeric immuno-modulatory compounds against cereblon-based mechanisms. WO2020014489A2. [2]. Rice DR, et al. Antiplasmodial activity of targeted zinc(II)-dipicolylamine complexes. Bioorg Med Chem. 2017 May 15;25(10):2754-2760. |