Bioactivity | Biotin-azide (N-(3-Azidopropyl)biotinamide) is a form of biotin with a terminal azide group. Biotin-azide can be used to prepare various biotinylated conjugates via Click Chemistry[1][2]. | ||||||||||||
Invitro | Click chemical functionalization postcrosslinking with a Biotin-azide probe enabled the isolation of transcriptional protein complexes from yeast cells[3]. | ||||||||||||
Name | Biotin-azide | ||||||||||||
CAS | 908007-17-0 | ||||||||||||
Formula | C13H22N6O2S | ||||||||||||
Molar Mass | 326.42 | ||||||||||||
Appearance | Solid | ||||||||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
Storage |
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Reference | [1]. Bruckman MA, et al. Tobacco mosaic virus-based protein nanoparticles and nanorods for chemotherapy delivery targeting breast cancer. J Control Release. 2016;231:103‐113. [2]. Kim HY, et al. An azido-biotin reagent for use in the isolation of protein adducts of lipid-derived electrophiles by streptavidin catch and photorelease. Mol Cell Proteomics. 2009;8(9):2080‐2089. [3]. Joiner CM, et al. A Bifunctional Amino Acid Enables Both Covalent Chemical Capture and Isolation of in Vivo Protein-Protein Interactions. Chembiochem. 2017 Jan 17;18(2):181-184. |