| Bioactivity | Antibacterial agent 90 (6n) is an antibacterial pleuromutilin derivative against Gram-positive pathogens (GPPs) and Mycoplasma pneumoniae[1]. |
| Invitro | Antibacterial agent 90 (6n) (0.0625 -128 µg/mL, 8 h) shows antibacterial activity with MICs of 0.0625, 0.5, 8, 0.125, 0.0625, and 0.5 µg/mL against MSSA, MRSA, E.faecium, M.pneumonia (ATCC15331), M.pneumonia (ATCC29342), and M.pneumonia (resistant strain, clinically isolated strain), respectively[1].Antibacterial agent 90 (0-10 µg/mL, 72 h) shows low cytotoxicity in human cancer cells[1].Antibacterial agent 90 exhibits good ADMET properties with high LogS, attractive ALogP, low PPB, non-Ames toxic, and non-carcinogenic[1]. Cell Cytotoxicity Assay[1] Cell Line: |
| Name | Antibacterial agent 90 |
| Formula | C30H42N2O6 |
| Molar Mass | 526.66 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Guangxu Wu, et al. Design, synthesis and antibacterial evaluation of pleuromutilin derivatives. Bioorg Med Chem. 2022 Apr 1;59:116676. |
Antibacterial agent 90
CAS: F: C30H42N2O6 W: 526.66
Antibacterial agent 90 (6n) is an antibacterial pleuromutilin derivative against Gram-positive pathogens (GPPs) and Myco
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