Antibacterial agent 220_product_DataBase

Bioactivity	Antibacterial agent 220 is a potent antibacterial agent that can directly destroy bacterial cell membranes. Antibacterial agent 220 effectively combats Gram-positive and and Gram-negative pathogens, including drug-resistant strains[1].
Invitro	Antibacterial agent 220 (compound 43) 具有较长的疏水链，对革兰氏阳性菌和革兰氏阴性菌均表现出强效抗菌活性，溶血活性较差（HC50>200 μg/mL）。Antibacterial agent 220 对金黄色葡萄球菌 ATCC29213、MRSA N315、MRSA NCTC10442 和大肠杆菌 ATCC25922 的 MIC 值分别为 1.56 μg/mL、0.78 μg/mL、0.78 μg/mL 和 6.25 μg/mL[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Antibacterial agent 220 相关抗体:
In Vivo	Antibacterial agent 220 (compound 43) 在小鼠角膜感染模型中表现出强大的体内抗菌功效[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model:
Formula	C37H54N8O8S
Molar Mass	770.94
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Rongcui Zhong, et al. Development of novel bisphenol derivatives with a membrane-targeting mechanism as potent gram-positive antibacterial agents. Eur J Med Chem. 2024 May 31:274:116544.

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